Spurs Ladies produced a champions-style performance - but had to wait until the second half for their rewards.
They dominated the first half but couldn't find the breakthrough as Ebbsfleet defended well.
Christina Oshodi came into the side and linked up with the wide players and Jenna Schillaci's deliveries were just missed by Rosi Webb and Robyn McEvoy.
Kelly Townsend came in for Rosi Webb at half-time and made an instant impact by heading home a corner for the opening goal.
Ebony Heath and Robin Downie dealt comfortably with what threat Ebbsfleet could muster going forward and it was left to a trademark free-kick from Emma Kayser to complete the scoreline.
Karen added: "I was very pleased with how the girls played, it was enjoyable to watch as they played with no fear and had the freedom in to try new things.
"It was also an opportunity for me to see a few of the other girls play that have been coming in an out of the side all season."